Three Challenges with Highly Multiplexed Spatial Proteomics in Clinical Tissue Samples
Canopy Biosciences' ChipCytometry platform is capable of extracting precise, spatially resolved, quantitative immunoprofiling data from clinical tissue samples. Clinical tissue specimens are largely prepared as formalin fixed, paraffin embedded (FFPE) blocks. FFPE presents unique challenges for those developing robust multiplexing assays. In this webinar, we discuss our strategies for dealing with three of these challenges: FFPE archived sample integrity, antigen retrieval or unmasking, and tissue autofluorescence.
From Mice to Men: Transition from Mouse Research to the Clinic
In this webinar, learn about the value and utilization of NanoString® nCounter® panels and the GeoMx® Digital Spatial Profiler (DSP) for preclinical studies that integrate bulk gene expression and spatial biology to maximize insight from precious samples.
Canopy & NanoString Spatial Biology Day
In this webinar, you'll hear from both Canopy and NanoString experts to learn more about NanoString’s GeoMx Digital Spatial Profiler (DSP).
GeoMx DSP combines the best of spatial and molecular profiling technologies by generating a whole tissue image at single cell resolution and digital profiling data for 10’s-1,000’s of RNA or Protein analytes from up to 12 tissue slides per day.
ChipCytometry: Software Update Tutorial #2
In this webinar, we will demonstrate the updated features of the ZellExplorer App, which includes several changes to the user interface and support system to improve your experience. Spencer Schwarz, Field Application Scientist, will give a demo.
How to Knockout a miRNA
CRISPR-Cas9 is a powerful DNA editing tool. However, the traditional approach to gene knockout with CRISPR-Cas9 does not result in KO of miRNAs and different strategies are required. In this 15-minute webinar, you will learn how these alternative strategies can be employed to knockout virtually any miRNA in your cell line.
ChipCytometry - Analysis of High-plex Proteomics in Tissue samples
ChipCytometry is an image-based proteomics platform that allows for quantitative analysis of protein biomarkers in tissues with true single-cell resolution and spatial context. In this webinar, we will discuss the basics of ChipCytometry and demonstrate the powerful image processing capabilities of high-plex data sets in tumor samples.
How to Separate the Signal from the Noise with Error-Corrected Sequencing
Standard NGS methodology has an error rate of 1-3%, making the detection of low-frequency variants difficult to decipher from the sequencing noise. For researchers studying clonal hematopoiesis it is critical to have an increased limit of detection to see mutated clonal populations. Recent studies have indicated these variants are present below the threshold of traditional sequencing strategies. RareSeq from Canopy Biosciences has been shown to be successful in identifying these mutated clonal populations sooner, potentially leading to better patient outcomes.
Multiplex Proteomics for Immune Profiling
In this 15-minute webinar, we will discuss different approaches multiplexed proteomic analysis for immune profiling of cells and tissues.
CLIA Certification in Biomarker Analysis Clinical Research
Most biomarker analysis works in Phase I and II clinical trials are exploratory clinical research studies. The data will then guide future clinical development or plan subsequent studies. With the clinical impact of this work, it's hard to know what level of lab certification you need— CLIA? GLP? GCP? CAP?
In this 15-minute webinar, we will discuss the lab certifications out there and help navigate who needs what for their level of lab research.
A Multi-Omic Approach to Immune Profiling
In this 15-minute webinar, we will discuss how different -omic technologies can be used together to profile immune cells present in a variety of sample types.
Common Pitfalls in Cell Line Editing with CRISPR-Cas9
In this 15-minute webinar, we will review the common problems researchers encounter when attempting to edit their cell line with CRISPR-Cas9 and how to overcome these challenges.
Clinical ChipCytometry - Biobanking PBMCs for Protein Biomarker Analysis in Clinical Trials
The ChipCytometry platform incorporates a revolutionary sample receptacle device called a ZellSafe Chip. This unique technology enables simple and reliable sample preservation that eliminates cryo-bias and allows for re-interrogation of precious clinical samples. In this webinar, we will discuss the advantages of employing ChipCytometry in clinical trials.
Why Highly Degraded Samples can Yield Highly Reproducible Results
With NanoString's digital counting technology, even highly degraded RNA yields high quality and highly reproducible results. FFPE is an extremely common sample—from research labs to clinical trials, there are FFPE samples everywhere. The challenge is how to analyze them. High variation, low yield, & high degradation makes them notoriously difficult. In this 15-minute webinar, learn how the robust nCounter gene expression assays have solved this issue allowing you to analyze up to 800 genes in a single sample.
In this 15-minute webinar, we will review the different types of ELISAs used for HCP detection in biologics. We will also give an overview on how to choose the best approach to find the right assay for your process.
How to Edit a Cell Line with CRISPR-Cas9
In this 15-minute webinar, we will discuss the basics of the CRISPR-Cas9 system. Learn how this powerful tool can be used to create knockouts, knock-ins, point mutations, and much more in commonly used cell lines.
ChipCytometry: Software Update Tutorial
In this 15-minute webinar, we will demonstrate the updated features of the ZellExplorer App, including new multi-gate display and hybrid scaling. Spencer Schwarz, Field Application Scientist, will give a live demo and answer any questions you might have about the new software features.
Pathogen Detection and Immune Response
This 15-minute webinar explores the forefront of developing treatments and understanding disease progression. With gene expression panels from NanoString, you can identify multiple species in a single sample and investigate the immune response of the host.
ChipCytometry: High-plex Proteomics
This 15-minute webinar discusses ChipCytometry–a powerful image-based multiplex cytometry technology. Through the immobilization of cells or tissue samples on fluidic chips, the technique can be used to analyze tissue samples or phenotype individual cells. We explore the importance of resolution, dynamic range, and robust data analysis to generate actionable data from ChipCytometry platforms.
Interactive Data Analysis Platform for NanoString
This 15-minute webinar explores Canopy Biosciences’ new interactive data analysis platform Rosalind. We provide an overview of the package we offer for data analysis of our NanoString + RNA-Seq services. Then we dive into a live demonstration of the interactive software so you can see its features highlighted.
NanoString — 800 Genes. 1 Sample.
This 11-minute webinar discusses our NanoString high throughput gene expression analysis service. The system is optimal for Oncology, Neuropathology, Infectious disease, and Immunological Research. NanoString works great with both fresh and FFPE tissue, blood, CSF, and isolated RNA. Receive a full data analysis report in a 2 week turn around time.
